TRPV6 anticorps (AA 620-764) (FITC)

N° du produit ABIN7172891

Détail du produit anti-TRPV6 anticorps (FITC)

Antigène: TRPV6 (Transient Receptor Potential Cation Channel, Subfamily V, Member 6 (TRPV6))

Épitope: AA 620-764

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRPV6 est conjugé à/à la FITC

Application: Veuillez nous consulter SVP

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Transient receptor potential cation channel subfamily V member 6 protein (620-764AA)

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TRPV6

Antigène: TRPV6 (Transient Receptor Potential Cation Channel, Subfamily V, Member 6 (TRPV6))

Autre désignation: TRPV6 (TRPV6 Produits)

Synonymes: anticorps ecac, anticorps trpv5-6, anticorps TRPV6, anticorps trpv6, anticorps CaT, anticorps ECaC, anticorps ABP/ZF, anticorps CAT1, anticorps CATL, anticorps ECAC2, anticorps HSA277909, anticorps LP6728, anticorps ZFAB, anticorps CAT, anticorps CaT1, anticorps Cac, anticorps Ecac2, anticorps Otrpc3, anticorps transient receptor potential cation channel, subfamily V, member 6, anticorps transient receptor potential cation channel subfamily V member 6, anticorps trpv6, anticorps TRPV6, anticorps Trpv6

Sujet:

Background: Calcium selective cation channel that mediates Ca(2+) uptake in various tissues, including the intestine (PubMed:11097838, PubMed:11278579, PubMed:11248124 PubMed:15184369, PubMed:23612980). Important for normal Ca(2+) ion homeostasis in the body, including bone and skin (By similarity). The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification (PubMed:15184369). Inactivation includes both a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin-dependent mechanism, the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.

Aliases: ABP/ZF antibody, ABPZF antibody, Alu binding protein with zinc finger domain antibody, Calcium channel CaT1 antibody, Calcium transport protein 1 antibody, CaT L antibody, CaT Like antibody, CaT-L antibody, CaT-like antibody, CaT1 antibody, ecac antibody, ECaC2 antibody, Epithelial apical membrane calcium transporter/channel CaT1 antibody, Epithelial calcium channel 2 antibody, Epithelial calcium channel antibody, HSA277909 antibody, LP6728 antibody, MGC162545 antibody, NUDC antibody, Transient receptor potential cation channel subfamily V member 6 antibody, TrpV6 antibody, TRPV6_HUMAN antibody, ZFAB antibody

UniProt: Q9H1D0

Pathways: TCR Signaling