RPS6KA1 anticorps (pThr348)

N° du produit ABIN713156

L’anticorps Lapin Polyclonal anti-RPS6KA1 a été validé pour WB, ELISA, IF (p), IF (cc), IHC (p) et IHC (fro). Il convient pour détecter RPS6KA1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour RPS6KA1 anticorps (pThr348) (ABIN713156)

Antigène: RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RPS6KA1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-RPS6KA1 anticorps

Épitope: pThr348

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human RPS6KA1 around the phosphorylation site of Thr348

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur RPS6KA1

Antigène: RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))

Autre désignation: RPS6KA1

Sujet:

Synonyms: p90RSKThr348, RPS6KA1phospho T348, p90 RSK1 , p90rsk , p90S6K , pp90RSK1 , Ribosomal protein S6 kinase 90kD 1 , Ribosomal protein S6 kinase 90kD polypeptide 1 , Ribosomal protein S6 kinase 90 kDa polypeptide 1 , Ribosomal protein S6 kinase alpha 1 , Ribosomal protein S6 kinase polypeptide 1 , Ribosomal S6 kinase 1 , RPS6K1 alpha , rps6ka , Rps6ka1 , RSK 1 , RSK 1 p90 , RSK , RSK1 , S6K alpha 1 , 90 kDa ribosomal protein S6 kinase 1 , dJ590P13.1 ribosomal protein S6 kinase, 90kD, polypeptide 1 , dJ590P13.1 , EC 2.7.11.1 , HU 1 , HU1 , MAP kinase activated protein kinase 1a , MAPKAP kinase 1A , MAPKAPK1A , MGC79981 , Mitogen-activated protein kinase-activated protein kinase 1A, KS6A1_HUMAN.

Background: Rsk1 is a member of a family of 90 kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine/threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c Fos and CREB.

ID gène: 6195

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades