CACNA1C anticorps (AA 1755-1971)

N° du produit ABIN7175586

Détail du produit anti-CACNA1C anticorps

Antigène: CACNA1C (Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C))

Épitope: AA 1755-1971

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CACNA1C est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Voltage-dependent L-type calcium channel subunit alpha-1C protein (1755-1971AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:200-1:500,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CACNA1C

Antigène: CACNA1C (Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C))

Autre désignation: CACNA1C (CACNA1C Produits)

Synonymes: anticorps CACH2, anticorps CACN2, anticorps CACNL1A1, anticorps CCHL1A1, anticorps CaV1.2, anticorps LQT8, anticorps TS, anticorps Cav1.2, anticorps Cchl1a1, anticorps MBC, anticorps MELC-CC, anticorps RATIVS302, anticorps isl, anticorps C-LTCC, anticorps CHCACHA1C, anticorps ICA, anticorps cav1.2, anticorps ca(v)1.2, anticorps CAV1.2, anticorps BCR, anticorps rbc, anticorps calcium voltage-gated channel subunit alpha1 C, anticorps calcium channel, voltage-dependent, L type, alpha 1C subunit, anticorps voltage-dependent L-type calcium channel subunit alpha-1C, anticorps calcium channel, voltage-dependent, L type, alpha 1C subunit S homeolog, anticorps Red blood cell count, anticorps RNA, 7SL, cytoplasmic 263, pseudogene, anticorps CACNA1C, anticorps Cacna1c, anticorps cacna1c, anticorps LOC100442085, anticorps cacna1c.S, anticorps RBC, anticorps RN7SL263P

Sujet:

Background: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1C gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the \\\'high-voltage activated\\\' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing the alpha-1C subunit play an important role in excitation-contraction coupling in the heart. The various isoforms display marked differences in the sensitivity to DHP compounds. Binding of calmodulin or CABP1 at the same regulatory sites results in an opposit effects on the channel function.

Aliases: alpha-1 polypeptide antibody, cardiac muscle antibody, isoform 1 antibody, L type antibody, CAC1C_HUMAN antibody, CACH 2 antibody, CACH2 antibody, CACN 2 antibody, CACN2 antibody, CACNA1C antibody, CACNL1A1 antibody, Calcium channel antibody, Calcium channel cardic dihydropyridine sensitive alpha 1 subunit antibody, Calcium channel L type alpha 1 polypeptide isoform 1 cardiac muscle antibody, Calcium channel voltage dependent L type alpha 1C subunit antibody, CaV1.2 antibody, CCHL1A1 antibody, DHPR alpha 1 antibody, DHPR alpha 1 subunit antibody, LQT8 antibody, TS antibody, Voltage dependent L type calcium channel alpha 1C subunit antibody, Voltage dependent L type calcium channel subunit alpha 1C antibody, Voltage gated calcium channel alpha subunit Cav1.2 antibody, Voltage gated calcium channel subunit alpha Cav1.2 antibody, Voltage gated L type calcium channel Cav1.2 alpha 1 subunit, splice variant 10* antibody, Voltage-dependent L-type calcium channel subunit alpha-1C antibody, Voltage-gated calcium channel subunit alpha Cav1.2 antibody

UniProt: Q13936

Pathways: Hormone Transport, Carbohydrate Homeostasis