LTK anticorps

N° du produit ABIN7183757

Détail du produit anti-LTK anticorps

Antigène: LTK (Leukocyte Receptor tyrosine Kinase (LTK))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LTK est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Humain, Souris

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from internal of Human LTK.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:3000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur LTK

Antigène: LTK (Leukocyte Receptor tyrosine Kinase (LTK))

Autre désignation: LTK (LTK Produits)

Synonymes: anticorps LTK, anticorps ALK, anticorps TYK1, anticorps si:dz107o16.1, anticorps leukocyte receptor tyrosine kinase, anticorps leukocyte tyrosine kinase, anticorps Ltk, anticorps LTK, anticorps ltk

Sujet:

Background: Orphan receptor with a tyrosine-protein kinase activity. The exact function of this protein is not known. Studies with chimeric proteins (replacing its extracellular region with that of several known growth factor receptors, such as EGFR and CSFIR) demonstrate its ability to promote growth and specifically neurite outgrowth, and cell survival. Signaling appears to involve the PI3 kinase pathway. Involved in regulation of the secretory pathway involving endoplasmic reticulum (ER) export sites (ERESs) and ER to Golgi transport.

Toyoshima H., Proc. Natl. Acad. Sci. U.S.A. 90:5404-5408(1993).
Krolewski J.J., EMBO J. 10:2911-2919(1991).
Maru Y., Oncogene Res. 5:199-204(1990).

Aliases: Leukocyte receptor tyrosine kinase antibody, Leukocyte tyrosine kinase antibody, Leukocyte tyrosine kinase receptor antibody, Ltk antibody, LTK_HUMAN antibody, Protein tyrosine kinase 1 antibody, TYK 1 antibody, TYK1 antibody

UniProt: P29376

Pathways: Signalisation RTK