DLC1 anticorps

N° du produit ABIN7184062

Détail du produit anti-DLC1 anticorps

Antigène: DLC1 (Deleted in Liver Cancer 1 (DLC1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DLC1 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Réactivité croisée: Humain, Souris

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from internal of Human RHG07.

Isotype: IgG

Information d'application

Indications d'application: IHC:1:50-1:100, IF:1:100-1:500,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur DLC1

Antigène: DLC1 (Deleted in Liver Cancer 1 (DLC1))

Autre désignation: DLC1 (DLC1 Produits)

Synonymes: anticorps ARHGAP7, anticorps HP, anticorps STARD12, anticorps p122-RhoGAP, anticorps rhogap7, anticorps DLC-1, anticorps StARD12, anticorps Dlc-1, anticorps A730069N07Rik, anticorps Arhgap7, anticorps dlc-1, anticorps RhoGAP, anticorps Dlc1, anticorps DLC1 Rho GTPase activating protein, anticorps DLC1 Rho GTPase activating protein S homeolog, anticorps rho GTPase-activating protein 7, anticorps deleted in liver cancer 1, anticorps DLC1, anticorps dlc1.S, anticorps dlc1, anticorps LOC100456847, anticorps Dlc1, anticorps LOC100729904

Sujet:

Background: Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.

Yuan B.Z., Cancer Res. 58:2196-2199(1998).
Nagase T., DNA Res. 7:347-355(2000).
Wilson P.J., Hum. Mutat. 15:156-165(2000).

Aliases: ARHGAP 7 antibody, ARHGAP7 antibody, Deleted in liver cancer 1 antibody, Deleted in liver cancer 1 protein antibody, DLC 1 antibody, Dlc-1 antibody, DLC1 antibody, DLC1 Rho GTPase activating protein antibody, FLJ21120 antibody, HP antibody, HP protein antibody, KIAA1723 antibody, p122 RhoGAP antibody, RHG07_HUMAN antibody, Rho GTPase activating protein 7 antibody, Rho GTPase-activating protein 7 antibody, Rho type GTPase activating protein 7 antibody, Rho-type GTPase-activating protein 7 antibody, StAR related lipid transfer (START) domain containing 12 antibody, StAR related lipid transfer protein 12 antibody, StAR-related lipid transfer protein 12 antibody, STARD 12 antibody, StARD12 antibody, START domain containing protein 12 antibody, START domain-containing protein 12 antibody

UniProt: Q96QB1

Pathways: Tube Formation, Positive Regulation of Endopeptidase Activity