PLG anticorps (N-Term)

N° du produit ABIN7184495

Cet anticorps Lapin Polyclonal détecte spécifiquement PLG dans WB et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour PLG anticorps (N-Term) (ABIN7184495)

Antigène: PLG (Plasminogen (PLG))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLG est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PLG anticorps

Épitope: N-Term

Fonction: PLG Antibody

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from N-terminal of Human PLG.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PLG

Antigène: PLG (Plasminogen (PLG))

Autre désignation: PLG

Sujet:

Background: Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells. Angiostatin is an angiogenesis inhibitor that blocks neovascularization and growth of experimental primary and metastatic tumors in vivo.

Petersen T.E., J. Biol. Chem. 265:6104-6111(1990).
Forsgren M., FEBS Lett. 213:254-260(1987).
Browne M.J., Submitted (OCT-1991) to the EMBL/GenBank/DDBJ databases.

Aliases: Plasmin antibody, Plasmin heavy chain A antibody, Plasmin light chain B antibody, Plasminogen antibody, PLG antibody, PLMN_HUMAN antibody

UniProt: P00747

Pathways: Système du Complément, Lipid Metabolism