SCN11A anticorps (Internal Region)

N° du produit ABIN7189376

Détail du produit anti-SCN11A anticorps

Antigène: SCN11A (Sodium Channel, Voltage-Gated, Type XI, alpha Subunit (SCN11A))

Épitope: Internal Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCN11A est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris, Rat

Purification: Antigen Affinity Purified

Immunogène: Synthetic peptide corresponding to a region derived from internal residues of Human sodium channel, voltage-gated, type XI, alpha subunit

Isotype: IgG

Information d'application

Indications d'application: IHC:1:50-1:100,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in pH 7.3 PBS, 0.05 % Sodium azide, 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SCN11A

Antigène: SCN11A (Sodium Channel, Voltage-Gated, Type XI, alpha Subunit (SCN11A))

Autre désignation: SCN11A (SCN11A Produits)

Synonymes: anticorps SCN11A, anticorps NSS2, anticorps NaN, anticorps NaT, anticorps SNS2, anticorps NAV1.9, anticorps SCN12A, anticorps SNS-2, anticorps sodium voltage-gated channel alpha subunit 11, anticorps sodium channel protein type 11 subunit alpha, anticorps sodium channel, voltage-gated, type XI, alpha, anticorps SCN11A, anticorps LOC100349709, anticorps Scn11a

Sujet:

Background: Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops, each domain consists of 6 transmembrane segments and intra- and extracellular linkers.

Aliases: hNaN antibody, NaN antibody, NAV1.9 antibody, Peripheral nerve sodium channel 5 antibody, PN 5 antibody, PN5 antibody, SCN 11A antibody, SCN 12A antibody, Scn11a antibody, SCN12A antibody, SCNBA_HUMAN antibody, Sensory neuron sodium channel 2 antibody, SNS 2 antibody, SNS2 antibody, Sodium channel protein type 11 subunit alpha antibody, Sodium channel protein type XI subunit alpha antibody, Sodium channel voltage gated type XI alpha antibody, Sodium channel voltage gated type XI alpha polypeptide antibody, Sodium channel voltage gated type XI alpha subunit antibody, Sodium channel voltage gated type XII alpha polypeptide antibody, Voltage gated sodium channel Nav1.9 antibody, Voltage gated sodium channel subunit alpha Nav1.9 antibody, Voltage-gated sodium channel subunit alpha Nav1.9 antibody

UniProt: Q9UI33