CKMT1A anticorps

N° du produit ABIN7190267

Détail du produit anti-CKMT1A anticorps

Antigène: CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CKMT1A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of Human CKMT1A/CKMT1B

Isotype: IgG

Information d'application

Indications d'application: ELISA:1:1000-1:5000, WB:1:1000-1:3000, IHC:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CKMT1A

Antigène: CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))

Autre désignation: CKMT1A (CKMT1A Produits)

Synonymes: anticorps CKMT1, anticorps Mt-CK, anticorps ScCKmit, anticorps UbCKmit, anticorps mi-CK, anticorps Ckmt1, anticorps CKMT1B, anticorps Mia-CK, anticorps U-MtCK, anticorps creatine kinase, mitochondrial 1A, anticorps creatine kinase U-type, mitochondrial-like, anticorps creatine kinase, mitochondrial 1, ubiquitous, anticorps creatine kinase U-type, mitochondrial, anticorps CKMT1A, anticorps LOC100228000, anticorps Ckmt1, anticorps LOC100725326

Sujet:

Background: Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80 % homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.

Aliases: Acidic-type mitochondrial creatine kinase antibody, CKMT antibody, CKMT1 antibody, CKMT1B antibody, Creatine kinase mitochondrial 1 (ubiquitous) antibody, Creatine kinase mitochondrial 1B antibody, Creatine kinase U type mitochondrial antibody, Creatine kinase U-type antibody, KCRU_HUMAN antibody, Mia-CK antibody, mitochondrial antibody, U-MtCK antibody, Ubiquitous mitochondrial creatine kinase antibody, UMTCK antibody

UniProt: P12532