KISS1 anticorps

N° du produit ABIN7191217

Détail du produit anti-KISS1 anticorps

Antigène: KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KISS1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain, Souris

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of Human KISS1

Isotype: IgG

Information d'application

Indications d'application: ELISA:1:1000-1:5000, WB:1:200-1:1000, IHC:1:5-1:20,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur KISS1

Antigène: KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))

Autre désignation: KISS1 (KISS1 Produits)

Synonymes: anticorps HH13, anticorps KiSS-1, anticorps metastatin, anticorps Eseptin, anticorps KiSS-1 metastasis-suppressor, anticorps KISS1, anticorps kiss1, anticorps Kiss1

Sujet:

Background: This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH nuerons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues.

Aliases: KISS 1 antibody, KiSS 1 metastasis suppressor antibody, Kiss1 antibody, KISS1_HUMAN antibody, Kisspeptin 1 antibody, Kisspeptin 10 antibody, Kisspeptin 13 antibody, Kisspeptin 14 antibody, Kisspeptin antibody, Kisspeptin-1 antibody, Kisspeptin-10 antibody, Kisspeptin-54 antibody, Kisspeptin1 antibody, Malignant melanoma metastasis suppressor antibody, Metastasis suppressor KiSS 1 antibody, Metastasis suppressor KiSS1 antibody, Metastin antibody, MGC39258 antibody

UniProt: Q15726

Pathways: Positive Regulation of Peptide Hormone Secretion