PTPRF anticorps (AA 1104-1163)

N° du produit ABIN7193270

Détail du produit anti-PTPRF anticorps

Antigène: PTPRF (Protein Tyrosine Phosphatase Receptor Type F (PTPRF))

Épitope: AA 1104-1163

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PTPRF est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), Neutralization (Neut)

Purification: purified

Immunogène: Purified recombinant fragment of human PTPRF (AA: extra 1104-1163) expressed in E. coli.

Clone: 6D7C7

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: N/A

Restrictions: For Research Use only

Stockage

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur PTPRF

Antigène: PTPRF (Protein Tyrosine Phosphatase Receptor Type F (PTPRF))

Autre désignation: PTPRF (PTPRF Produits)

Synonymes: anticorps LAR, anticorps AA591035, anticorps LARS, anticorps RPTP-LAR, anticorps LARFN5C, anticorps zf-LAR, anticorps protein tyrosine phosphatase, receptor type F, anticorps protein tyrosine phosphatase, receptor type, F, anticorps protein tyrosine phosphatase, receptor type, f, a, anticorps PTPRF, anticorps Ptprf, anticorps ptprfa

Sujet:

Description: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.

Aliases: LAR, BNAH2

Poids moléculaire: 213 kDa

ID gène: 5792

Pathways: EGFR Signaling Pathway