CLEC7A anticorps (AA 66-247)

N° du produit ABIN7193336

Détail du produit anti-CLEC7A anticorps

Antigène: CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))

Épitope: AA 66-247

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CLEC7A est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Neutralization (Neut)

Purification: purified

Immunogène: Purified recombinant fragment of human CD369 (AA: extra 66-247) expressed in E. coli.

Clone: 4G2G6

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: N/A, ICC: 1:200 - 1:1000

Restrictions: For Research Use only

Stockage

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur CLEC7A

Antigène: CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))

Autre désignation: CD369 (CLEC7A Produits)

Synonymes: anticorps CLEC7A, anticorps BGR, anticorps Clecsf12, anticorps beta-GR, anticorps CANDF4, anticorps CLECSF12, anticorps DECTIN1, anticorps Clec7b, anticorps RGD1565140, anticorps C-type lectin domain containing 7A, anticorps C-type lectin domain family 7, member a, anticorps CLEC7A, anticorps Clec7a

Sujet:

Description: This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Aliases: CLEC7A, BGR, CANDF4, SCARE2, DECTIN1, CLECSF12

Poids moléculaire: 27.6 kDa

ID gène: 64581

Pathways: Activation of Innate immune Response