CLEC7A anticorps (PE)

N° du produit ABIN7505928

Détail du produit anti-CLEC7A anticorps (PE)

Antigène: CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CLEC7A est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Fonction: Anti-Hu CD369 PE

Specificité: The mouse monoclonal antibody 15E2 recognizes an extracellular epitope LWEDGSTFSSN of human CD369 (Dectin-1), a 33 kDa transmembrane glycoprotein expressed predominantly on dendritic cells.

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogène: Extracellular part of human CD369 with hIgG FC tag

Clone: 15E2

Isotype: IgG2a kappa

Information d'application

Indications d'application: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Stockage

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Détails sur CLEC7A

Antigène: CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))

Autre désignation: CD369 (CLEC7A Produits)

Synonymes: anticorps CLEC7A, anticorps BGR, anticorps Clecsf12, anticorps beta-GR, anticorps CANDF4, anticorps CLECSF12, anticorps DECTIN1, anticorps Clec7b, anticorps RGD1565140, anticorps C-type lectin domain containing 7A, anticorps C-type lectin domain family 7, member a, anticorps CLEC7A, anticorps Clec7a

Sujet: C-type lectin domain containing 7A,CD369 (dectin-1, beta-glucan receptor) is a 33 kDa type II transmembrane glycoprotein of lectin family, and serves as a part of innate immunity system by binding to beta-glucan polymers, which are typical for yeast and mycobacterial cell walls. CD369 is expressed predominantly on dendritic cells, but it can be detected also on monocytes, macrophages, mast cells, eosinophils, B cells, endothelial cells, and sometimes also on some T cell subsets.,Dectin-1, CLEC7A, BGR, CANDF4, SCARE2

ID gène: 64581

UniProt: Q9BXN2

Pathways: Activation of Innate immune Response