LILRB4 anticorps (AA 22-259)

N° du produit ABIN7193750

Détail du produit anti-LILRB4 anticorps

Antigène: LILRB4 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 4 (LILRB4))

Épitope: AA 22-259

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LILRB4 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Purification: purified

Immunogène: Purified recombinant fragment of human CD85K (AA: 22-259) expressed in E. coli.

Clone: 8F1H11

Isotype: IgG1

Information d'application

Indications d'application: WB:1:500 - 1:2000, IHC:1:200 - 1:1000, ICC:1:200 - 1:1000, FCM:1:200 - 1:400, ELISA:1:10000,

Restrictions: For Research Use only

Stockage

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur LILRB4

Antigène: LILRB4 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 4 (LILRB4))

Autre désignation: CD85K (LILRB4 Produits)

Synonymes: anticorps CD85K, anticorps ILT-3, anticorps ILT3, anticorps LIR-5, anticorps LIR5, anticorps Gp49b, anticorps HM18, anticorps gp49, anticorps leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4, anticorps leukocyte immunoglobulin like receptor B4, anticorps leukocyte immunoglobulin-like receptor, subfamily B, member 4A, anticorps LILRB4, anticorps Lilrb4a

Sujet:

Description: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Aliases: ILT3, LIR5, LILRB4, ILT-3, LIR-5

Poids moléculaire: 49 kDa

ID gène: 11006