JAK1 anticorps (AA 960-1040)

N° du produit ABIN7212172

L’anticorps anti-JAK1 Monoclonal Souris est utilisé pour la détection de JAK1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour IHC et IF.

Aperçu rapide pour JAK1 anticorps (AA 960-1040) (ABIN7212172)

Antigène: JAK1 (Janus Kinase 1 (JAK1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp JAK1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: 7G6

Détail du produit anti-JAK1 anticorps

Épitope: AA 960-1040

Fonction: Mouse Anti-JAK1 Mouse Monoclonal Antibody (7G6)

Specificité: JAK1 protein detects endogenous levels of JAK1.

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogène: Synthetic Peptide of JAK1 at AA range of 960-1040

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-200,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur JAK1

Antigène: JAK1 (Janus Kinase 1 (JAK1))

Autre désignation: JAK1

Sujet: JAK1JAK1 (Janus kinase 1) encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 130kD

ID gène: 3716

UniProt: P23458

Pathways: Signalistation JAK/STAT, Signalisation RTK, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response