5HT1B Receptor anticorps (AA 180-260)
Aperçu rapide pour 5HT1B Receptor anticorps (AA 180-260) (ABIN7221612)
Antigène
Voir toutes 5HT1B Receptor (HTR1B) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 180-260
-
Fonction
- Rabbit Anti-SR-1B Polyclonal Antibody
-
Specificité
- SR-1B Polyclonal Antibody detects endogenous levels of SR-1B protein.
-
Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
Immunogène
- Synthesized peptide derived from the Internal region of human SR-1B at AA range: 180-260
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
Date de péremption
- 12 months
-
-
- 5HT1B Receptor (HTR1B) (Serotonin Receptor 1B (HTR1B))
-
Autre désignation
- SR-1B
-
Sujet
- HTR1B, HTR1DB, 5-hydroxytryptamine receptor 1B, 5-HT-1B, 5-HT1B, S12, Serotonin 1D beta receptor, 5-HT-1D-beta, Serotonin receptor 1BThe 5-hydroxytryptamine receptor 1B encoded by HTR1B is a G-protein coupled receptor for serotonin (5-hydroxytryptamine). Ligand binding activates second messengers that inhibit the activity of adenylate cyclase and manage the release of serotonin, dopamine, and acetylcholine in the brain. The encoded protein may be involved in several neuropsychiatric disorders and therefore is often a target of antidepressant and other psychotherapeutic drugs.
-
Poids moléculaire
- 43kD
-
ID gène
- 3351
-
UniProt
- P28222
-
Pathways
- Signalistation JAK/STAT, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, S100 Proteins
Antigène
-