ABCA1 anticorps (AA 1870-2120)

N° du produit ABIN7265726

Détail du produit anti-ABCA1 anticorps

Antigène: ABCA1 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))

Épitope: AA 1870-2120

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABCA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Fonction: ABCA1 Rabbit pAb

Séquence: IQYRFFIRPR PVNAKLSPLN DEDEDVRRER QRILDGGGQN DILEIKELTK IYRRKRKPAV DRICVGIPPG ECFGLLGVNG AGKSSTFKML TGDTTVTRGD AFLNKNSILS NIHEVHQNMG YCPQFDAITE LLTGREHVEF FALLRGVPEK EVGKVGEWAI RKLGLVKYGE KYAGNYSGGN KRKLSTAMAL IGGPPVVFLD EPTTGMDPKA RRFLWNCALS VVKEGRSVVL TSHSMEECEA LCTRMAIMVN G

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1870-2120 of human ABCA1 (NP_005493.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ABCA1

Antigène: ABCA1 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))

Autre désignation: ABCA1 (ABCA1 Produits)

Synonymes: anticorps ABC-1, anticorps ABC1, anticorps CERP, anticorps HDLDT1, anticorps TGD, anticorps ABCA1, anticorps Abc1, anticorps ATP-binding cassette A1, anticorps Arabidopsis thaliana ATP-binding cassette A1, anticorps AtABCA1, anticorps im:7136239, anticorps sb:cb407, anticorps wu:fa07e06, anticorps zgc:171581, anticorps ATP binding cassette subfamily A member 1, anticorps ATP-binding cassette, sub-family A (ABC1), member 1, anticorps ATP-binding cassette A1, anticorps ATP-binding cassette, sub-family A (ABC1), member 1B, anticorps ABCA1, anticorps Abca1, anticorps abca1, anticorps abca1b

Sujet: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.,ABCA1;ABC-1;ABC1;CERP;HDLDT1;TGD,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Neuroscience,Cell Type Marker,Cardiovascular,Heart,Lipids,Cardiovascular diseases,Heart disease,Astrocyte marker,ABCA1

Poids moléculaire: 254kDa

ID gène: 19

UniProt: O95477

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism