ATP11C anticorps (AA 430-650)

N° du produit ABIN7265757

Détail du produit anti-ATP11C anticorps

Antigène: ATP11C (ATPase, class VI, type 11C (ATP11C))

Épitope: AA 430-650

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP11C est non-conjugé

Application: Western Blotting (WB)

Fonction: ATP11C Rabbit pAb

Séquence: DGHKYKGVTQ EVDGLSQTDG TLTYFDKVDK NREELFLRAL CLCHTVEIKT NDAVDGATES AELTYISSSP DEIALVKGAK RYGFTFLGNR NGYMRVENQR KEIEEYELLH TLNFDAVRRR MSVIVKTQEG DILLFCKGAD SAVFPRVQNH EIELTKVHVE RNAMDGYRTL CVAFKEIAPD DYERINRQLI EAKMALQDRE EKMEKVFDDI ETNMNLIGAT A

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 430-650 of human ATP11C (NP_775965.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ATP11C

Antigène: ATP11C (ATPase, class VI, type 11C (ATP11C))

Autre désignation: ATP11C (ATP11C Produits)

Synonymes: anticorps A330005H02Rik, anticorps AI315324, anticorps Ig, anticorps Atp11c-ps1, anticorps RGD1564481, anticorps ATPase, class VI, type 11C, anticorps ATPase phospholipid transporting 11C, anticorps Atp11c

Sujet: Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids, phosphatidylserines (PS and phosphatidylethanolamines (PE, from the outer to the inner leaflet of the plasma membrane. Major PS-flippase in immune cell subsets. In erythrocyte plasma membrane, it is required to maintain PS in the inner leaflet preventing its exposure on the surface. This asymmetric distribution is critical for the survival of erythrocytes in circulation since externalized PS is a phagocytic signal for erythrocyte clearance by splenic macrophages. Required for B cell differentiation past the pro-B cell stage (By similarity. Seems to mediate PS flipping in pro-B cells (By similarity. May be involved in the transport of cholestatic bile acids (By similarity.,ATP11C,ATPIG,ATPIQ,Signal Transduction,Endocrine & Metabolism,Immunology & Inflammation,ATP11C

Poids moléculaire: 126kDa/128kDa/129kDa

ID gène: 286410

UniProt: Q8NB49