EGFR anticorps (pTyr1173)

N° du produit ABIN7266989

L’anticorps Lapin Monoclonal anti-EGFR a été validé pour WB. Il convient pour détecter EGFR dans des échantillons de Humain.

Aperçu rapide pour EGFR anticorps (pTyr1173) (ABIN7266989)

Antigène: EGFR (Epidermal Growth Factor Receptor (EGFR))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp EGFR est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-EGFR anticorps

Épitope: pTyr1173

Fonction: Phospho-EGFR-Y1173 Rabbit mAb

Réactivité croisée: Humain

Attributs du produit: Phosphorylated Antibodies

Purification: Affinity purification

Immunogène: A phospho specific peptide corresponding to residues surrounding Y1173 of human EGFR

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur EGFR

Antigène: EGFR (Epidermal Growth Factor Receptor (EGFR))

Autre désignation: EGFR

Sujet: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016],ERBB, ERBB1, HER1, NISBD2, PIG61, mENA,Angiogenesis,Cancer,Cardiovascular,Cell Biology & Developmental Biology,ErbB-HER Signaling Pathway,G protein signaling,Growth factors,Growth factors_EGF,IL-6 Receptor Signaling Pathway,Immunology & Inflammation,Kinase,Kinase_Tyrosine kinases,Phospholipase Signaling Pathway,Protein phosphorylation,Signal Transduction,Tumor biomarkers,EGFR

Poids moléculaire: 175kDa

ID gène: 1956

UniProt: P00533

Pathways: Signalisation NF-kappaB, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins