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- Antigène Voir toutes FGL1 Anticorps
- FGL1 (Fibrinogen-Like 1 (FGL1))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp FGL1 est non-conjugé
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Application
- Western Blotting (WB)
- Fonction
- FGL1 Rabbit mAb
- Réactivité croisée
- Humain
- Attributs du produit
- Monoclonal Antibodies
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of human FGL-1 Full length.
- Isotype
- IgG
- Top Product
- Discover our top product FGL1 Anticorps primaire
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anti-Fibrinogen-Like 1 (FGL1) (AA 23-314) antibody
FGL1 Reactivité: Rat WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Fibrinogen-Like 1 (FGL1) (AA 23-312) antibodyFGL1 Reactivité: Humain WB, IHC, ELISA, ICC, FACS Hôte: Souris Monoclonal 4F9C11 unconjugated
anti-Fibrinogen-Like 1 (FGL1) (AA 23-312) antibodyFGL1 Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Fibrinogen-Like 1 (FGL1) (AA 19-312) antibodyFGL1 Reactivité: Humain WB, ELISA, IP Hôte: Souris Monoclonal 2A4 unconjugated
anti-Fibrinogen-Like 1 (FGL1) (AA 23-314) antibodyFGL1 Reactivité: Souris WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Fibrinogen-Like 1 (FGL1) (AA 23-312) antibodyFGL1 Reactivité: Humain WB, IHC, IP, ICC Hôte: Souris Monoclonal C5 unconjugated
anti-Fibrinogen-Like 1 (FGL1) (AA 179-282) antibodyFGL1 Reactivité: Humain WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
anti-Fibrinogen-Like 1 (FGL1) (AA 218-247), (C-Term) antibodyFGL1 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB19507 unconjugated
anti-Fibrinogen-Like 1 (FGL1) antibodyFGL1 Reactivité: Humain, Souris, Rat WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
anti-Fibrinogen-Like 1 (FGL1) (AA 1-312) antibodyFGL1 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
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- Indications d'application
- WB,1:500 - 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.09 % sodium azide,50 % glycerol, pH 7.4.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- FGL1 (Fibrinogen-Like 1 (FGL1))
- Autre désignation
- FGL1 (FGL1 Produits)
- Synonymes
- anticorps MGC84748, anticorps FGL1, anticorps DKFZp470A2333, anticorps Frep1, anticorps Lfire1, anticorps HFREP1, anticorps HP-041, anticorps LFIRE-1, anticorps LFIRE1, anticorps Mfire1, anticorps fibrinogen like 1 L homeolog, anticorps fibrinogen like 1, anticorps fibrinogen-like 1, anticorps fibrinogen-like protein 1, anticorps fgl1.L, anticorps FGL1, anticorps Fgl1
- Sujet
- Fibrinogen-like protein 1 (FGL1), a liver-secreted protein, is a major LAG-3 functional ligand independent from MHC-II. The FGL1-LAG-3 pathway maybe an important immune evasion mechanism and could contribute to current cancer immunotherapy efforts for several reasons. FGL1 inhibits antigen-specific T cell activation, and ablation of FGL1 in mice promotes T cell immunity. Blockade of the FGL1-LAG-3 interaction by monoclonal antibodies stimulates tumor immunity and is therapeutic against established mouse tumors in a receptor-ligand inter-dependent manner. FGL1 is highly produced by human cancer cells, and elevated FGL1 in the plasma of cancer patients is associated with a poor prognosis and resistance to anti-PD-1/B7-H1 therapy,FGL1,HFREP1,HP-041,LFIRE-1,LFIRE1,Cardiovascular,Blood,Coagulation,Serum Proteins,FGL1
- Poids moléculaire
- 36kDa
- ID gène
- 2267
- UniProt
- Q08830
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