GCH1 anticorps (AA 1-250)

N° du produit ABIN7267525

Détail du produit anti-GCH1 anticorps

Antigène: GCH1 (GTP Cyclohydrolase 1 (GCH1))

Épitope: AA 1-250

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GCH1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Fonction: GCH1 Rabbit pAb

Séquence: MEKGPVRAPA EKPRGARCSN GFPERDPPRP GPSRPAEKPP RPEAKSAQPA DGWKGERPRS EEDNELNLPN LAAAYSSILS SLGENPQRQG LLKTPWRAAS AMQFFTKGYQ ETISDVLNDA IFDEDHDEMV IVKDIDMFSM CEHHLVPFVG KVHIGYLPNK QVLGLSKLAR IVEIYSRRLQ VQERLTKQIA VAITEALRPA GVGVVVEATH MCMVMRGVQK MNSKTVTSTM LGVFREDPKT REEFLTLIRS

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human GCH1 (NP_000152.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GCH1

Antigène: GCH1 (GTP Cyclohydrolase 1 (GCH1))

Autre désignation: GCH1 (GCH1 Produits)

Synonymes: anticorps DYT14, anticorps DYT5, anticorps DYT5a, anticorps GCH, anticorps GTP-CH-1, anticorps GTPCH1, anticorps HPABH4B, anticorps GTP-CH, anticorps GTPCH, anticorps Gch, anticorps MGC89622, anticorps gch1a, anticorps wu:fc16b10, anticorps zgc:195269, anticorps GTP cyclohydrolase 1, anticorps GTP cyclohydrolase 1-like, anticorps GCH1, anticorps Gch1, anticorps gch1, anticorps Weevi_1190, anticorps Halhy_0838, anticorps Sinme_1220, anticorps Sphch_1077, anticorps LOC100136794

Sujet: This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described, however, not all variants give rise to a functional enzyme.,GCH1,DYT14,DYT5,DYT5a,GCH,GTP-CH-1,GTPCH1,HPABH4B,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Amino acid metabolism,Neuroscience,GCH1

Poids moléculaire: 23kDa/25kDa/27kDa

ID gène: 2643

UniProt: P30793