IDO1 anticorps

N° du produit ABIN7267863

Détail du produit anti-IDO1 anticorps

Antigène: IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp IDO1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Fonction: IDO1 Rabbit mAb

Réactivité croisée: Humain, Souris

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human IDO1

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur IDO1

Antigène: IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

Autre désignation: IDO1 (IDO1 Produits)

Synonymes: anticorps INDO, anticorps ido, anticorps indo, anticorps IDO, anticorps cd107b, anticorps IDO1, anticorps IDO-1, anticorps Ido, anticorps Indo, anticorps indoleamine 2,3-dioxygenase 1, anticorps indoleamine 2,3-dioxygenase 1 L homeolog, anticorps indoleamine 2,3-dioxygenase 1-like, anticorps IDO1, anticorps ido1.L, anticorps ido1, anticorps Ido1, anticorps LOC100050681

Sujet: This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011],IDO, IDO-1, INDO,Amino acid metabolism,Cancer,Cardiovascular,Endocrine & Metabolism,Immunology & Inflammation,Signal Transduction,IDO1

Poids moléculaire: 45kDa

ID gène: 3620

UniProt: P14902

Pathways: Activated T Cell Proliferation