NLRP1 anticorps (AA 1000-1100)

N° du produit ABIN7268935

Cet anticorps Lapin Polyclonal détecte spécifiquement NLRP1 dans WB, IHC et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour NLRP1 anticorps (AA 1000-1100) (ABIN7268935)

Antigène: NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-NLRP1 anticorps

Épitope: AA 1000-1100

Fonction: NLRP1 Rabbit pAb

Séquence: TGEMSNSTSS LKRQRLGSER AASHVAQANL KLLDVSKIFP IAEIAGKSHE ESSPEVVPVE LLCVPSPASQ GDLHTKPLGT DDDFWGPTGP VATEVVDKEK N

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 1000-1100 of human NLRP1 (NP_001028225.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NLRP1

Antigène: NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))

Autre désignation: NLRP1

Sujet: This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.,NLRP1,AIADK,CARD7,CIDED,CLR17.1,DEFCAP,DEFCAP-L/S,MSPC,NAC,NALP1,PP1044,SLEV1,VAMAS1,Cell Biology & Developmental Biology,Apoptosis,Caspases,NLRP1

Poids moléculaire: 46kDa/83kDa/154-165kDa

ID gène: 22861

UniProt: Q9C000

Pathways: Positive Regulation of Endopeptidase Activity, Inflammasome