NLRP6 anticorps (AA 100-200)

N° du produit ABIN7268941

Cet anticorps Lapin Polyclonal détecte spécifiquement NLRP6 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour NLRP6 anticorps (AA 100-200) (ABIN7268941)

Antigène: NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-NLRP6 anticorps

Épitope: AA 100-200

Fonction: NLRP6 Rabbit pAb

Séquence: RRLQRLGLGS GTLLSVSEYK KKYREHVLQL HARVKERNAR SVKITKRFTK LLIAPESAAP EEAMGPAEEP EPGRARRSDT HTFNRLFRRD EEGRRPLTVV L

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human NLRP6 (NP_001263629.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NLRP6

Antigène: NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

Autre désignation: NLRP6

Sujet: The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene.,NLRP6,AVR,CLR11.4,NALP6,NAVR,NAVR/AVR,PAN3,PYPAF5,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Caspases,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,NLRP6

Poids moléculaire: 99kDa

ID gène: 171389

UniProt: P59044

Pathways: Inflammasome