NRF2 anticorps (pSer40)

N° du produit ABIN7268970

Cet anticorps anti-NRF2 est un anticorps Lapin Monoclonal détectant NRF2 dans WB et IHC. Adapté pour Humain.

Aperçu rapide pour NRF2 anticorps (pSer40) (ABIN7268970)

Antigène: NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp NRF2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-NRF2 anticorps

Épitope: pSer40

Fonction: Phospho-NRF2-S40 Rabbit mAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Phosphorylated Antibodies

Purification: Affinity purification

Immunogène: A phospho specific peptide corresponding to residues surrounding S40 of human NRF2

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NRF2

Antigène: NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

Autre désignation: NFE2L2

Sujet: This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters, many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene. [provided by RefSeq, Sep 2015],HEBP1, NRF2,Cardiovascular,Cell Biology & Developmental Biology,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,Heart,Heart_Cardiac metabolism,Mitochondrial metabolism,Mitochondrial metabolism_Mitochondrial Biogenesis,Nucleotide metabolism,Nucleotide metabolism_Molecular processes,Transcription Factors,NFE2L2

Poids moléculaire: 90kDa

ID gène: 4780

UniProt: Q16236

Pathways: ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling