PAX5 anticorps

N° du produit ABIN7269154

Détail du produit anti-PAX5 anticorps

Antigène: PAX5 (Paired Box 5 (PAX5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp PAX5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Fonction: PAX5 Rabbit mAb

Réactivité croisée: Humain

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human PAX5

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PAX5

Antigène: PAX5 (Paired Box 5 (PAX5))

Autre désignation: PAX5 (PAX5 Produits)

Synonymes: anticorps PAX5, anticorps BSAP, anticorps Pax-5, anticorps pax5-a, anticorps RGD1565236, anticorps EBB-1, anticorps KLP, anticorps Pax[Zf-b], anticorps noi, anticorps pax2.1, anticorps pax2a, anticorps paxzf-b, anticorps paired box 5, anticorps paired box 5 L homeolog, anticorps PAX5, anticorps pax5.L, anticorps Pax5, anticorps pax5

Sujet: This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. Paired box transcription factors are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9,14)(p13,q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013],ALL3, BSAP,Epigenetics & Nuclear Signaling,Neuroscience,Transcription Factors,PAX5

Poids moléculaire: 45kDa

ID gène: 5079

UniProt: Q02548