PCGF2 anticorps

N° du produit ABIN7269450

Détail du produit anti-PCGF2 anticorps

Antigène: PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCGF2 est non-conjugé

Application: Western Blotting (WB)

Fonction: PCGF2 Rabbit pAb

Réactivité croisée: Humain, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant protein of human PCGF2.

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PCGF2

Antigène: PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))

Autre désignation: PCGF2 (PCGF2 Produits)

Synonymes: anticorps ZNF144, anticorps PCGF2, anticorps MEL-18, anticorps RNF110, anticorps Mel18, anticorps Rnf110, anticorps Zfp144, anticorps mel-18, anticorps polycomb group ring finger 2, anticorps PCGF2, anticorps Pcgf2

Sujet: The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses.,PCGF2,MEL-18,RNF110,ZNF144,Epigenetics & Nuclear Signaling,Chromatin Remodeling,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Ubiquitin,Stem Cells,Hematopoietic Progenitors,PCGF2

Poids moléculaire: 38kDa

ID gène: 7703

UniProt: P35227

Pathways: Chromatin Binding