SRRT anticorps (AA 623-872)

N° du produit ABIN7270253

Détail du produit anti-SRRT anticorps

Antigène: SRRT (Serrate RNA Effector Molecule Homolog (SRRT))

Épitope: AA 623-872

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SRRT est non-conjugé

Application: Immunohistochemistry (IHC)

Fonction: SRRT Rabbit pAb

Séquence: DYYNTCEYPN EDEMPNRCGI IHVRGPMPPN RISHGEVLEW QKTFEEKLTP LLSVRESLSE EEAQKMGRKD PEQEVEKFVT SNTQELGKDK WLCPLSGKKF KGPEFVRKHI FNKHAEKIEE VKKEVAFFNN FLTDAKRPAL PEIKPAQPPG PAQSLTPGLP YPHQTPQGLM PYGQPRPPIL GYGAGAVRPA VPTGGPPYPH APYGAGRGNY DAFRGQGGYP GKPRNRMVRG DPRAIVEYRD LDAPDDVDFF

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 623-872 of human SRRT (NP_001122325.1).

Isotype: IgG

Information d'application

Indications d'application: IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SRRT

Antigène: SRRT (Serrate RNA Effector Molecule Homolog (SRRT))

Autre désignation: SRRT (SRRT Produits)

Synonymes: anticorps CG7843, anticorps Dmel\\CG7843, anticorps anon-WO0118547.166, anticorps ars2, anticorps ars2-A, anticorps serrate, anticorps ARS2, anticorps ASR2, anticorps 2810019G02Rik, anticorps ASR2A, anticorps ASR2B, anticorps ASR2C, anticorps ASR2D, anticorps Ars2, anticorps Asr2, anticorps MGC92060, anticorps CHUNP6881, anticorps zgc:92060, anticorps Arsenic resistance protein 2, anticorps serrate, RNA effector molecule S homeolog, anticorps serrate, RNA effector molecule, anticorps serrate RNA effector molecule homolog (Arabidopsis), anticorps Ars2, anticorps srrt.S, anticorps SRRT, anticorps Srrt, anticorps srrt

Sujet: Acts as a mediator between the cap-binding complex (CBC and the primary microRNAs (miRNAs processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi by miRNAs. Binds capped RNAs (m7GpppG-capped RNA, however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity. Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity.,SRRT,ARS2,ASR2,serrate,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Drug metabolism,SRRT

Poids moléculaire: 96kDa/100kDa

ID gène: 51593

UniProt: Q9BXP5

Pathways: Signalisation Notch, Stem Cell Maintenance