TTLL12 anticorps

N° du produit ABIN7271032

Détail du produit anti-TTLL12 anticorps

Antigène: TTLL12 (Tubulin tyrosine Ligase-Like Family, Member 12 (TTLL12))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TTLL12 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Fonction: [KO Validated] TTLL12 Rabbit pAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Classe de qualité: KO Validated

Immunogène: Recombinant protein of human TTLL12.

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TTLL12

Antigène: TTLL12 (Tubulin tyrosine Ligase-Like Family, Member 12 (TTLL12))

Autre désignation: TTLL12 (TTLL12 Produits)

Synonymes: anticorps zgc:55343, anticorps dJ526I14.2, anticorps RGD1305319, anticorps BC055368, anticorps D430005B17, anticorps tubulin tyrosine ligase-like family, member 12, anticorps tubulin tyrosine ligase like 12, anticorps Tubulin--tyrosine ligase-like protein 12, anticorps ttll12, anticorps TTLL12, anticorps ttll-12, anticorps Ttll12

Sujet: Negatively regulates post-translational modifications of tubulin, including detyrosination of the C-terminus and polyglutamylation of glutamate residues. Also, indirectly promotes histone H4 trimethylation at 'Lys-20' (H4K20me3. Probably by controlling tubulin and/or histone H4 post-translational modifications, plays a role in mitosis and in maintaining chromosome number stability. During RNA virus-mediated infection, acts as a negative regulator of the DDX58/RIG-I pathway by preventing MAVS binding to TBK1 and IKBKE.,TTLL12,dJ526I14.2,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microtubules,TTLL12

Poids moléculaire: 74kDa

ID gène: 23170

UniProt: Q14166