ERBB4 anticorps

N° du produit ABIN7271256

Cet anticorps anti-ERBB4 Monoclonal Lapin (ABIN7271256) détecte spécifiquement ERBB4 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ERBB4 anticorps (ABIN7271256)

Antigène: ERBB4 (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp ERBB4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ERBB4 anticorps

Fonction: ErbB4/HER4 Rabbit mAb

Réactivité croisée: Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human ErbB4/HER4

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ERBB4

Antigène: ERBB4 (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4))

Autre désignation: ERBB4

Sujet: This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008],ALS19,HER4,p180erbB4,ERBB4,HER4/ErbB4,Cancer,Cell Biology & Developmental Biology,ErbB-HER Signaling Pathway,Growth factors,Growth factors_EGF,Immunology & Inflammation,Kinase,Kinase_Tyrosine kinases,Protein phosphorylation,Signal Transduction,Tumor biomarkers,ERBB4

Poids moléculaire: 160kDa

ID gène: 2066

UniProt: Q15303

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway