DMBT1 anticorps

N° du produit ABIN7384267

Détail du produit anti-DMBT1 anticorps

Antigène: DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DMBT1 est non-conjugé

Application: Immunohistochemistry (IHC)

Purification: Antigen Affinity Purification

Immunogène: Recombinant Human Deleted in malignant brain tumors 1 protein

Isotype: IgG

Information d'application

Indications d'application: IHC 1:200-1:500

Restrictions: For Research Use only

Stockage

Concentration: 0.71 mg/mL

Buffer: PBS with 0.05 % Proclin300, 50 % glycerol, pH 7.3.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DMBT1

Antigène: DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))

Autre désignation: DMBT1 (DMBT1 Produits)

Synonymes: anticorps GP340, anticorps muclin, anticorps CRP, anticorps CRP-[a], anticorps CRP-[b], anticorps Crpd, anticorps DBMT1, anticorps gp300, anticorps p80, anticorps DMBT1, anticorps gp340, anticorps deleted in malignant brain tumors 1, anticorps deleted in malignant brain tumors 1 protein, anticorps gp340, anticorps deleted in malignant brain tumors 1 S homeolog, anticorps DMBT1, anticorps Dmbt1, anticorps LOC100064515, anticorps dmbt1, anticorps ST201phi2-1p340, anticorps dmbt1.S

Sujet: Apactin, CRP, Crpd, DBMT1, Deleted in malignant brain tumors 1 protein, DMBT1, DMBT1 prototype precursor, Ebnerin, FLJ61058, Glycoprotein 300, Glycoprotein 340, GP340, Gp340 variant protein, GP340, Hensin, MGC164738, Muclin, p80, Pancrin, SAG, Salivary agglutinin, Surfactant pulmonary associated D binding protein, Vomeroglandin,Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. The gene DMBT1 was originally isolated based on its deletion in a medulloblastoma cell line. DMBT1 is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The DMBT1 protein is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor suppressor gene, but rather play a role in the interaction of tumor cells and the immune system.

ID gène: 1755

UniProt: Q9UGM3

Pathways: Activation of Innate immune Response