SMG7 anticorps (Internal Region)

N° du produit ABIN7384295

Détail du produit anti-SMG7 anticorps

Antigène: SMG7 (Smg-7 Homolog, Nonsense Mediated mRNA Decay Factor (SMG7))

Épitope: Internal Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMG7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Affinity purification

Immunogène: Synthesized peptide derived from the Internal region of human SMG7

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SMG7

Antigène: SMG7 (Smg-7 Homolog, Nonsense Mediated mRNA Decay Factor (SMG7))

Autre désignation: SMG7 (SMG7 Produits)

Synonymes: anticorps 9430023P16Rik, anticorps mKIAA0250, anticorps C1orf16, anticorps EST1C, anticorps SGA56M, anticorps Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans), anticorps SMG7, nonsense mediated mRNA decay factor, anticorps Smg7, anticorps SMG7

Sujet: Breast cancer-associated antigen SGA-56M,C1orf16,EST1 like protein C,EST1 telomerase component homolog C,EST1-like protein C,EST1C,ever shorter telomeres 1C,FLJ23717,hSMG-7,nonsense mediated mRNA decay factor (C. elegans),Protein SMG7,SGA56M,SMG 7,SMG-7 homolog,Smg7,SMG7,This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD), a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms.SMG7 (SMG7, Nonsense Mediated MRNA Decay Factor) is a Protein Coding gene. Among its related pathways are Gene Expression and Viral mRNA Translation. GO annotations related to this gene include protein phosphatase 2A binding. An important paralog of this gene is SMG6.

Poids moléculaire:

Observed_MW: 127kDa

Calculated_MW: 127kDa

ID gène: 9887

UniProt: Q92540