c-MYC anticorps

N° du produit ABIN7384328

Cet anticorps Lapin Monoclonal détecte spécifiquement c-MYC dans WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour c-MYC anticorps (ABIN7384328)

Antigène: c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp c-MYC est non-conjugé

Application: Western Blotting (WB)

Clone: R05-5E2

Détail du produit anti-c-MYC anticorps

Purification: Affinity Purified

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-1:2000

Restrictions: For Research Use only

Stockage

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur c-MYC

Antigène: c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Autre désignation: c Myc

Sujet: AU016757,Avian myelocytomatosis viral oncogene homolog,bHLHe39,c Myc,Class E basic helix-loop-helix protein 39,MRTL,Myc,Myc protein,Myc proto oncogene protein,Myc proto-oncogene protein,myc-related translation/localization regulatory factor,MYC,Myc2,MYCC,Myelocytomatosis oncogene,Niard,Nird,Oncogene Myc,OTTHUMP00000158589,Proto-oncogene c-Myc,Protooncogene homologous to myelocytomatosis virus,RNCMYC,Transcription factor p64,Transcriptional regulator Myc-A,V-Myc avian myelocytomatosis viral oncogene homolog,v-myc myelocytomatosis viral oncogene homolog (avian),This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.

Poids moléculaire:

Observed_MW: 57-65kDa

Calculated_MW: 49kDa

ID gène: 4609

UniProt: P01106

Pathways: Signalisation p53, Cycle Cellulaire, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, L'effet Warburg