s100a4 anticorps
Aperçu rapide pour s100a4 anticorps (ABIN7384491)
Antigène
Voir toutes s100a4 (S100A4) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Purification
- Affinity Purified
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Isotype
- IgG
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Indications d'application
- WB 1:1000-1:2000 IHC 1:50-1:100
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Restrictions
- For Research Use only
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Concentration
- 300 μg/mL
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Buffer
- 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- s100a4 (S100A4) (S100 Calcium Binding Protein A4 (S100A4))
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Autre désignation
- S100A4
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Sujet
- 18A2,42A,calcium Placental protein,Calvasculin,CAPL,Fibroblast specific protein 1 (FSP1),Fibroblast specific protein 1,Fibroblast specific protein,FSP1,Leukemia multidrug resistance associated protein,Malignant transformation suppression 1 (MTS1),Malignant transformation suppression 1,Metastasin,MTS1,OTTHUMP00000015467,OTTHUMP00000015468,P9KA,PEL98,Placental calcium-binding protein,Protein Mts1,Protein S100 A4,Protein S100-A4,S100 calcium binding protein A4 (calcium protein,calvasculin,metastasin,murine placental homolog),S100 calcium binding protein A4,S100 calcium-binding protein A4,S100a4,S10A4,S100A4 is a member of the S100 family of calcium-binding proteins. The S100 family members have been involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A4 is known to localize to and function in the nucleus, cytoplasm of cells and the extracellular space. S100A4 has also been shown to be associated with tumor growth, motility, invasion, metastasis, angiogenesis, apoptosis and chemoresistance. It is a fibroblast-specific protein associated with mesenchymal cell morphology and motility, is expressed during epithelial-mesenchymal transformations (EMT) in vivo. It is an improved marker for lung fibroblasts that could be useful for investigating the pathogenesis of pulmonary fibrosis. Overexpression of S100A4 is correlated with a worse prognosis inpatients with various types of cancer.
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Poids moléculaire
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Observed_MW: 12kDa
Calculated_MW: 12kDa
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ID gène
- 6275
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UniProt
- P26447
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Pathways
- S100 Proteins
Antigène
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