BRAF anticorps (AA 25-75)

N° du produit ABIN7448439

Cet anticorps anti-BRAF est un anticorps Lapin Polyclonal détectant BRAF dans IHC. Adapté pour Humain.

Aperçu rapide pour BRAF anticorps (AA 25-75) (ABIN7448439)

Antigène: BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BRAF est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-BRAF anticorps

Épitope: AA 25-75

Fonction: Rabbit anti-BRAF IHC Antibody, Affinity Purified

Homologie: Mouse,Rat,Bovine,Dog,Gorilla,Chimpanzee,Crab-eating macaque,White-tufted-ear marmoset,Northern white-cheeked gibbon,Small-eared galago

Purification: Affinity Purified

Immunogène: Between AA 25 and 75

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur BRAF

Antigène: BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))

Autre désignation: BRAF

Sujet: Background: B-Raf proto-oncogene serine/threonine-protein kinase (BRAF) is a member of the raf/mil family of serine/threonine kinases. BRAF is involved in transducing mitogenic signals via the MAP kinase/ERKs signaling pathway. Mutations in BRAF are involved in a wide range of cancers such as lung, non-Hodgkin lymphoma, and colorectal cancer. Defects in BRAF are also the cause of cardiofaciocutaneous syndrome (CFC), an autosomal dominant syndrome characterized by facial anomalies, heart defects, and ectodermal abnormalities.

ID gène: 673

NCBI Accession: NP_004324

UniProt: P15056

Pathways: Signalisation MAPK, Signalisation RTK, Neurotrophin Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagy