MEK1 anticorps (AA 343-393)

N° du produit ABIN7448664

Cet anticorps anti-MEK1 est un anticorps Polyclonal produit chez le Lapin, détectant MEK1 dans IHC. Convient pour Humain.

Aperçu rapide pour MEK1 anticorps (AA 343-393) (ABIN7448664)

Antigène: MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MEK1 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-MEK1 anticorps

Épitope: AA 343-393

Fonction: Rabbit anti-MEK1 IHC Antibody, Affinity Purified

Homologie: X. laevis,X. tropicalis,Chicken,Turkey,Bovine,Dog,Horse,Rabbit,Pig,Panda,Monkey,Gorilla,Chimpanzee,Crab-eating macaque,White-tufted-ear marmoset,West Indian ocean coelacanth,Duckbill platypus,Small-eared galago,African elephant,Zebra finch,Little brown bat,Island canary,Thirteen-lined ground squirrel,Northern white-cheeked gibbon

Purification: Affinity Purified

Immunogène: Between AA 343 and 393

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur MEK1

Antigène: MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))

Autre désignation: MEK1

Sujet: Background: MEK1 is an activator and kinase for MAP and ERK kinases. It is a serine/threonine kinase essential to the MAP kinase signal transduction pathway which is involved in a multitude of cellular processes such as proliferation, differentiation, gene activation, and development. MEK1 displays 85 % identity with MEK2. Although MEK1 and MEK2 have been found to be functionally similar, they may serve non-redundant functions. Both are required for cellular proliferation and may play a role in tumorigenesis.

ID gène: 5604

NCBI Accession: NP_002746

UniProt: Q02750

Pathways: Signalisation MAPK, Signalisation RTK, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling