TRAF2 anticorps (AA 175-225)

N° du produit ABIN7450839

Cet anticorps anti-TRAF2 est un anticorps Lapin Polyclonal détectant TRAF2 dans WB et IP. Adapté pour Humain.

Aperçu rapide pour TRAF2 anticorps (AA 175-225) (ABIN7450839)

Antigène: TRAF2 (TNF Receptor-Associated Factor 2 (TRAF2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRAF2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-TRAF2 anticorps

Épitope: AA 175-225

Fonction: Rabbit anti-TRAF2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 175 and 225

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur TRAF2

Antigène: TRAF2 (TNF Receptor-Associated Factor 2 (TRAF2))

Autre désignation: TRAF2

Sujet: Background: TNF receptor-associated factor 2 (TRAF2) regulates activation of NF-kappa-B and JNK and plays a central role in the regulation of cell survival and apoptosis. TRAF2 is required for normal antibody isotype switching from IgM to IgG. TRAF2 has E3 ubiquitin-protein ligase activity and promotes 'Lys-63'-linked ubiquitination of target proteins, such as BIRC3, RIPK1 and TICAM1. TRAF2 is an essential constituent of several E3 ubiquitin-protein ligase complexes, where it promotes the ubiquitination of target proteins by bringing them into contact with other E3 ubiquitin ligases [taken from the Universal Protein Resource (UniProt) Q12933].

ID gène: 7186

NCBI Accession: NP_066961

UniProt: Q12933

Pathways: Signalisation NF-kappaB, Apoptose, Caspase Cascade in Apoptosis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Unfolded Protein Response, S100 Proteins