SOS1 anticorps (AA 1025-1075)
Aperçu rapide pour SOS1 anticorps (AA 1025-1075) (ABIN7452439)
Antigène
Voir toutes SOS1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1025-1075
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Fonction
- Rabbit anti-SOS1 Antibody, Affinity Purified
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Homologie
- Mouse
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Purification
- Affinity Purified
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Immunogène
- between AA 1025 and 1075
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Isotype
- IgG
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Indications d'application
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-SOS1 antibody ABIN7452055.
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Date de péremption
- 12 months
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- SOS1 (Son of Sevenless Homolog 1 (SOS1))
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Autre désignation
- SOS1
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Sujet
- Background: SOS1 (son of sevenless homolog 1) is a human paralog of the drosophila SOS gene. Drosophila SOS was originally identified as a gene that functioned downstream of the sevenless gene in the Ras/MAP kinase signaling pathway. SOS and its paralogs, SOS1 and SOS2, function as guanine nucleotide exchange factors that act on Ras-GTPases to cause release of GDP in exchange for GTP. Mutations in SOS1 are the cause of Noonan syndrome type 4 and gingival fibromatosis.
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ID gène
- 6654
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NCBI Accession
- NP_005624
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UniProt
- Q07889
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Pathways
- Signalisation RTK, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
Antigène
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