MAP3K7 anticorps (AA 250-300)

N° du produit ABIN7452450

Cet anticorps anti-MAP3K7 Polyclonal Lapin (ABIN7452450) détecte spécifiquement MAP3K7 dans IP. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour MAP3K7 anticorps (AA 250-300) (ABIN7452450)

Antigène: MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP3K7 est non-conjugé

Application: Immunoprecipitation (IP)

Détail du produit anti-MAP3K7 anticorps

Épitope: AA 250-300

Fonction: Rabbit anti-TAK1 Antibody, Affinity Purified

Homologie: Mouse,Rat,Bovine,Orangutan

Purification: Affinity Purified

Immunogène: between AA 250 and 300

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-TAK1 antibody ABIN7452087.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur MAP3K7

Antigène: MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))

Autre désignation: TAK1

Sujet: Background: TAK1 (TGF-beta activated kinase 1) is also called mitogen-activated protein kinase kinase kinase 7 (MAP3K7). TAK1 is a serine/threonine protein kinase that mediates signals transduced by proinflammatory cytokines such as TGF-beta, tumor necrosis factor (TNF), interleukin-1 (IL-1) and wnt family ligands. TAK1 transduces signals by stimulating a MAPK pathway that ultimately stimulates JNK (c-terminal jun kinase) and p38 MAPKs. TAK1 is also an activator of the Ikappa B kinase that leads to the activation of NFkappa-B.

ID gène: 6885

NCBI Accession: NP_663304

UniProt: O43318

Pathways: Signalisation NF-kappaB, TCR Signaling, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway