SPTY2D1 anticorps (AA 75-125)
SPTY2D1
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
unconjugated
-
- Antigène Tous les produits SPTY2D1
- SPTY2D1 (SPT2, Suppressor of Ty, Domain Containing 1 (SPTY2D1))
- Épitope
- AA 75-125
- Reactivité
- Humain
- Hôte
- Lapin
- Clonalité
- Polyclonal
- Application
- Western Blotting (WB)
- Fonction
- Rabbit anti-SPTY2D1 Antibody, Affinity Purified
- Homologie
- Mouse
- Purification
- Affinity Purified
- Immunogène
- Between AA 75 and 125
- Isotype
- IgG
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- Indications d'application
-
IP: Not recommended
WB: 1:1,000 - 1:5,000
- Restrictions
- For Research Use only
-
- Concentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Date de péremption
- 12 months
-
- Antigène
- SPTY2D1 (SPT2, Suppressor of Ty, Domain Containing 1 (SPTY2D1))
- Autre désignation
- SPTY2D1 (SPTY2D1 Produits)
- Synonymes
- anticorps 5830435K17Rik, anticorps AI852426, anticorps P16H6, anticorps SPT2 chromatin protein domain containing 1, anticorps SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae), anticorps SPTY2D1, anticorps Spty2d1
- Sujet
- Background: SPT2, Suppressor of Ty (SPTY2D1) is a histone chaperone that stabilizes pre-existing histone tetramers and regulates replication-independent histone exchange on chromatin (PubMed:26109053). It is required for normal chromatin refolding in the coding region of transcribed genes, and for the suppression of spurious transcription (PubMed:26109053). SPTY2D1 binds DNA and histones and promotes nucleosome assembly (in vitro) (PubMed:23378026, PubMed:26109053). It facilitates formation of tetrameric histone complexes containing histone H3 and H4 (PubMed:26109053). SPTY2D1 modulates RNA polymerase 1-mediated transcription (By similarity) and binds DNA, with a preference for branched DNA species, such as Y-form DNA and Holliday junction DNA (PubMed:23378026) [taken from the Universal Protein Resource (UniProt) Q68D10].
- ID gène
- 144108
- UniProt
- Q68D10
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