PSMB5 anticorps (AA 213-263)

N° du produit ABIN7453445

Détail du produit anti-PSMB5 anticorps

Antigène: PSMB5 (Proteasome (Prosome, Macropain) Subunit, beta Type, 5 (PSMB5))

Épitope: AA 213-263

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMB5 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Fonction: Rabbit anti-PSMB5 Antibody, Affinity Purified

Homologie: Orangutan

Purification: Affinity Purified

Immunogène: Between AA 213 and 263

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PSMB5

Antigène: PSMB5 (Proteasome (Prosome, Macropain) Subunit, beta Type, 5 (PSMB5))

Autre désignation: PSMB5 (PSMB5 Produits)

Synonymes: anticorps LMPX, anticorps MB1, anticorps X, anticorps etID309919.2, anticorps fb59c07, anticorps si:zc14a17.13, anticorps wu:fb59c07, anticorps x, anticorps zgc:86820, anticorps proteasome subunit beta 5, anticorps proteasome (prosome, macropain) subunit, beta type 5, anticorps proteasome subunit beta 5 L homeolog, anticorps proteasome (prosome, macropain) subunit, beta type, 5, anticorps PSMB5, anticorps psmb5, anticorps Psmb5, anticorps psmb5.L

Sujet: Background: PSMB5 [proteasome (prosome, macropain) subunit, beta type, 5)] is a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit) [taken from NCBI Entrez Gene (Gene ID: 5693)].

ID gène: 5693

NCBI Accession: NP_002788

UniProt: P28074

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA