Mre11 anticorps (AA 658-708)

N° du produit ABIN7454999

Cet anticorps anti-Mre11 est un anticorps Lapin Polyclonal détectant Mre11 dans WB, IP et IHC (fp). Adapté pour Humain.

Aperçu rapide pour Mre11 anticorps (AA 658-708) (ABIN7454999)

Antigène: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Mre11 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-Mre11 anticorps

Épitope: AA 658-708

Fonction: Rabbit anti-Mre11 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 658 and 708

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Mre11

Antigène: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Autre désignation: Mre11

Sujet: Background: Mre11 is a component of the MRN complex and plays a role in telomere maintenance and double-strand break (DSB) repair. Mre11 associates with rad50 in the MRN complex. Mre11 possesses 3'- 5' exonuclease activity that is involved in creating DNA termini in DSB suitable for priming DNA synthesis and ligation.

ID gène: 4361

NCBI Accession: NP_005582

UniProt: P49959

Pathways: Réparation de l'ADN