Recombinant STAT5B anticorps (AA 737-787)

N° du produit ABIN7455110

Cet anticorps anti-STAT5B est un anticorps Lapin Monoclonal détectant STAT5B dans WB, IP, ICC et IHC (fp). Adapté pour Humain et Souris.

Aperçu rapide pour Recombinant STAT5B anticorps (AA 737-787) (ABIN7455110)

Antigène: STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp STAT5B est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: BLR146J

Détail du produit anti-STAT5B anticorps

Épitope: AA 737-787

Fonction: Rabbit anti-STAT5b Recombinant Monoclonal Antibody [BLR146J]

Immunogène: between AA 737 and 787 (C-term)

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 6 μL/1 mg lysate

ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

WB: 01:01,00

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur STAT5B

Antigène: STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))

Autre désignation: STAT5b

Sujet: Background: Signal transducer and activator of transcription 5b (STAT5b) is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT5A mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression [taken from NCBI Entrez Gene (Gene ID: 6777)].

ID gène: 6777

NCBI Accession: NP_036580

UniProt: P51692

Pathways: Signalistation JAK/STAT, Signalisation RTK, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation