IL4 Receptor anticorps

N° du produit ABIN7490587

Cet anticorps Lapin Chimeric détecte spécifiquement IL4 Receptor dans FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour IL4 Receptor anticorps (ABIN7490587)

Antigène: IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))

Fragment: Fc fragment

Reactivité: Humain

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp IL4 Receptor est non-conjugé

Application: Flow Cytometry (FACS)

Détail du produit anti-IL4 Receptor anticorps

Attributs du produit: Rabbit/Human Fc chimeric IgG1

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Information d'application

Indications d'application: Flow Cyt  1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détails sur IL4 Receptor

Antigène: IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))

Autre désignation: IL4RA

Sujet: CD124, IL-4RA, IL4RA,
Description: This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.

UniProt: P24394

Pathways: Signalistation JAK/STAT, Positive Regulation of Immune Effector Process