p21 (RAC1) Activated Kinase 6 (PAK6) (N-Term) anticorps
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- Antigène
- p21 (RAC1) Activated Kinase 6 (PAK6)
- Épitope
- N-Term
- Reactivité
- Humain
- Hôte
- Lapin
- Clonalité
- Polyclonal
- Application
- Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
- Réactivité croisée
- Humain
- Purification
- Purified by antigen-affinity chromatography.
- Immunogène
- Recombinant protein encompassing a sequence within the N-terminus region of human PAK6. The exact sequence is proprietary.
- Isotype
- IgG
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- Indications d'application
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- Agent conservateur
- Thimerosal (Merthiolate)
- Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
- Antigène
- p21 (RAC1) Activated Kinase 6 (PAK6)
- Autre désignation
- p21 (RAC1) activated kinase 6
- Synonymes
- anticorps PAK5, anticorps p21 (RAC1) activated kinase 6, anticorps PAK6
- Sujet
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Synonyms: p21 (RAC1) activated kinase 6 , PAK5
Background: This gene encodes a member of the p21-activated kinase (PAK) family. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. This gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
- Poids moléculaire
- 75 kDa
- ID gène
- 56924
- UniProt
- Q9NQU5
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