PSMB7 anticorps

N° du produit ABIN7468791

Détail du produit anti-PSMB7 anticorps

Antigène: PSMB7 (Proteasome (Prosome, Macropain) Subunit, beta Type, 7 (PSMB7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMB7 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Réactivité croisée: Humain, Souris

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human Proteasome 20S beta 7. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: Mouse brain , HepG2

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur PSMB7

Antigène: PSMB7 (Proteasome (Prosome, Macropain) Subunit, beta Type, 7 (PSMB7))

Autre désignation: proteasome subunit beta 7 (PSMB7 Produits)

Synonymes: anticorps DDBDRAFT_0185624, anticorps DDBDRAFT_0232933, anticorps DDB_0185624, anticorps DDB_0232933, anticorps AU020723, anticorps MC14, anticorps Z, anticorps 20S proteasome subunit beta-7, anticorps proteasome (prosome, macropain) subunit, beta type, 7 S homeolog, anticorps proteasome subunit beta 7, anticorps proteasome (prosome, macropain) subunit, beta type, 7, anticorps proteasome (prosome, macropain) subunit, beta type 7, anticorps psmB7, anticorps psmb7.S, anticorps PSMB7, anticorps Psmb7

Sujet:

Synonyms: proteasome subunit beta 7 , Z

Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon and proteolytic processing is required to generate a mature subunit. This subunit is not present in the immunoproteasome and is replaced by catalytic subunit 2i (proteasome beta 10 subunit). [provided by RefSeq]

Poids moléculaire: 30 kDa

ID gène: 5695

UniProt: Q99436

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA