HVEM anticorps

N° du produit ABIN7505890

Détail du produit anti-HVEM anticorps

Antigène: HVEM (TNFRSF14) (Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HVEM est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Fonction: Anti-Hu CD270 Purified

Specificité: The mouse monoclonal antibody CW10 recognizes an extracellular epitope on CD270, a type I transmembrane protein expressed on resting T cells, monocytes, and immature dendritic cells.

Purification: Purified by protein-A affinity chromatography.

Immunogène: recombinant human CD270

Clone: CW10

Isotype: IgG1 kappa

Information d'application

Indications d'application: Flow cytometry: Recommended dilution: 1-5 μg/mL.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détails sur HVEM

Antigène: HVEM (TNFRSF14) (Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14))

Autre désignation: CD270 (TNFRSF14 Produits)

Synonymes: anticorps ATAR, anticorps CD270, anticorps HVEA, anticorps HVEM, anticorps LIGHTR, anticorps TR2, anticorps Atar, anticorps HveA, anticorps Hvem, anticorps Tnfrs14, anticorps TNF receptor superfamily member 14, anticorps tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator), anticorps Tnfrsf14, anticorps TNFRSF14

Classe de substances: Viral Protein

Sujet: TNF receptor superfamily member 14,CD270 is a type I transmembrane protein of the TNFR superfamily, which is expressed on resting T cells, monocytes, and immature dendritic cells. Its ligands, CD258 and CD272, differ in effect on CD270 signaling. Whereas binding to CD258 provides a costimulatory signal, binding to CD272 gives to the cell an inhibitory signal. CD270 also is recognized by herpes simplex glycoprotein D. CD258-CD270 interaction and signaling is implicated in macrophage-derived foam cell-mediated development of atherosclerotic lesions.,TNFRSF14, TR2, ATAR, HVEA, HVEM, LIGHTR

ID gène: 8764

UniProt: Q92956

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints