The mouse monoclonal antibody AYP1 recognizes an epitope within the extracellular part of CLEC2, a transmembrane glycoprotein expressed on activated plateles and on platelet microparticles.
Purification
Purified by protein-A affinity chromatography.
Immunogène
A recombinant extracellular domain of human CLEC2 (amino acids 68-229)
anticorps 1810061I13Rik, anticorps CLEC2, anticorps CLEC2B, anticorps PRO1384, anticorps QDED721, anticorps Clec-2, anticorps Clec2, anticorps CLEC1B, anticorps RGD1563517, anticorps CLEC9A, anticorps C-type lectin domain family 1 member B, anticorps C-type lectin domain family 1, member b, anticorps C-type lectin domain family 1, member B, anticorps CLEC1B, anticorps Clec1b
Classe de substances
Viral Protein
Sujet
C-type lectin domain family 1 member B,CLEC2 (C-type lectin-like receptor 2) functions as a platelet receptor for the lymphatic endothelial marker, PDPN, and mediates platelet activation. Besides platelets, it can be found on myeloid cells and NK cells. CLEC2 functions also as an attachment factor for HIV-1 and facilitates its capture by platelets. Platelet-aggregating snake venom protein rhodocytin also binds to CLEC2.,CLEC1B, CLEC2B, PRO1384, QDED721