Mre11 anticorps (AA 182-582)

N° du produit ABIN7539803

Cet anticorps anti-Mre11 Monoclonal Souris (Clone 4D2B6) (ABIN7539803) détecte spécifiquement Mre11 dans IHC, ELISA et FACS. L’anticorps est réactif avec des échantillons de Humain et Rat.

Aperçu rapide pour Mre11 anticorps (AA 182-582) (ABIN7539803)

Antigène: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Mre11 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Clone: 4D2B6

Détail du produit anti-Mre11 anticorps

Épitope: AA 182-582

Fonction: MRE11 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human MRE11 (AA: 182-582) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur Mre11

Antigène: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Autre désignation: MRE11

Sujet: This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog, this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Poids moléculaire: 80.6 kDa

ID gène: 4361

UniProt: P49959

Pathways: Réparation de l'ADN