CENPF anticorps (AA 129-3078)

N° du produit ABIN7599912

L’anticorps Lapin Polyclonal anti-CENPF a été validé pour ELISA, WB, IF, ICC et FACS. Il convient pour détecter CENPF dans des échantillons de Humain.

Aperçu rapide pour CENPF anticorps (AA 129-3078) (ABIN7599912)

Antigène: CENPF (Centromere Protein F (CENPF))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CENPF est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Détail du produit anti-CENPF anticorps

Épitope: AA 129-3078

Fonction: Anti-CENPF Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-CENPF Antibody Picoband® (ABIN7599912). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human CENPF recombinant protein (Position: Q129-R3078).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Filges, I., Bruder, E., Brandal, K., Meier, S., Undlien, D. E., Waage, T. R., Hoesli, I., Schubach, M., de Beer, T., Sheng, Y., Hoeller, S., Schulzke, S., Rosby, O., Miny, P., Tercanli, S., Oppedal, T., Meyer, P., Selmer, K. K., Stromme, P. Stromme syndrome is a ciliary disorder caused by mutations in CENPF. Hum. Mutat. 37: 359-363, 2016. Note: Erratum: Hum. Mutat. 37: 711 only, 2016. 2. Fowler, K. J., Saffery, R., Irvine, D. V., Trowell, H. E., Choo, K. H. A. Mouse centromere protein F (Cenpf) gene maps to the distal region of chromosome 1 by interspecific backcross analysis. Cytogenet. Cell Genet. 82: 180-181, 1998. 3. Gross, M. B. Personal Communication. Baltimore, Md. 8/24/2016.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur CENPF

Antigène: CENPF (Centromere Protein F (CENPF))

Autre désignation: CENPF

Sujet:

Synonyms: Glutathione S-transferase Mu 3, GST class-mu 3, GSTM3-3, hGSTM3-3, GSTM3, GST5,

Tissue Specificity: Testis and brain.

Background: Centromere protein F is a protein that in humans is encoded by the CENPF gene. This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease.

Poids moléculaire: 358 kDa

ID gène: 1063

UniProt: P49454

Pathways: Chromatin Binding, M Phase, SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2