PAK1 anticorps (AA 2-248)

N° du produit ABIN7600479

Cet anticorps Lapin Polyclonal détecte spécifiquement PAK1 dans WB et ELISA. Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour PAK1 anticorps (AA 2-248) (ABIN7600479)

Antigène: PAK1 (P21-Activated Kinase 1 (PAK1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAK1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PAK1 anticorps

Épitope: AA 2-248

Fonction: Anti-PAK1 Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-PAK1 Antibody (ABIN7600479). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PAK1 recombinant protein (Position: S2-M248).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur PAK1

Antigène: PAK1 (P21-Activated Kinase 1 (PAK1))

Autre désignation: PAK1

Sujet:

Synonyms: Neutrophil gelatinase-associated lipocalin,NGAL,Lipocalin-2,SV-40-induced 24P3 protein,Siderocalin LCN2,p25,Lcn2,

Tissue Specificity: Detected in lung, spleen, uterus, vagina and epididymis. .

Background: Serine/threonine-protein kinase PAK 1 is an enzyme that in humans is encoded by the PAK1 gene. PAK proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activated kinases, include PAK1, PAK2, PAK3 and PAK4. These proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK1 regulates cell motility and morphology. Alternative transcripts of this gene have been found, but their full-length natures have not yet been determined. The PAK1 gene is mapped to 11q13-q14 by inclusion within a mapped clone.

Poids moléculaire: 66 kDa

ID gène: 5058

UniProt: Q13153

Pathways: Signalisation MAPK, Signalisation RTK, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Embryonic Body Morphogenesis